Description
benefits.html
Ingredients
Science
Testimonials
Company
Home Purchase Other Resources Natures Sunshine Products
Ask the Herbalist
Zambroza Ingredients
Mangosteen Raspberry
Wolfberry Blueberry
Sea Buckthorn Apple Extract
Grape Seed Extract Green Tea

Scientists at Nature's Sunshine began studying the mangosteen fruit in the fall of 2003. They found that although mangosteen does have amazing potential as a supplement, it does not have a complete Antioxidant Profile. They found that by adding additional fruits and fruit extracts to mangosteen they could boost its antioxidant power and increase its Antioxidant Profile by many times. The result is a supplement that not only tastes great but has incredible ability to neutralize Free Radicals throughout the body. There are many types of antioxidants. What scientists have discovered is antioxidants work synergistically, the more different kinds of antioxidants you consume the more powerful their ability to neutralize Free Radicals.

In an independent study by Brunswick Laboratories, Zambroza was found to have extremely high ORAC (Oxygen Radical Absorbance Capacity) levels. This independent laboratory, verified the overwhelming superiority of Zambroza's antioxidant levels over other supplements in an industry-standard test. This ORAC test verifies the potency of the xanthones, phenols, bioflavonoids, and other powerful antioxidants.

 

Zambroza's exotic taste comes from these eleven nutrient rich foods, bursting with antioxidant power. Here is more information of each of Zambroza's Ingredients:

 

Mangosteen (Garcinia mangostana)

The highest source of a family of antioxidants called xanthones which support the immune system and circulatory system.

            As the gentle rains fall on the islands of South-East Asia, mangosteen groves soak in the nutrients of the rich jungle soil.  These nutrients help create one of the most unique fruits ever discovered.  Mangosteen, also called the "Queen of Fruits" is prized by natives of these islands, not only for its taste but its ability to give energy and as a powerful traditional medicine.  Native islanders have used this exotic fruit for thousands of years but its healing properties have only just been discovered by western scientists.  Modern clinical studies confirm that Mangosteen is a potent source of antioxidants (which help the body guard against free radical damage1,2), and contain other ingredients that help support the immune, cardiovascular systems, and give the body extra energy. 

Mangosteen contains a class of antioxidants called xanthones which help the body build a healthy immune and cardiovascular system. Xanthones3 have attracted attention from scientists and researchers who are investigating how these compounds support the immune system, structural system, digestive system, brain, and the skin. Mangosteen offers one of the greatest known supplies of xanthones.  

 

1J Nat Prod. 2003 Aug;66(8):1124-7  Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines.  Matsumoto K, Akao Y, Kobayashi E, Ohguchi K, Ito T, Tanaka T, Iinuma M 

 

2 Planta Med. 2002 Nov;68(11):975-9 Garcinone E, a xanthone derivative, has potent cytotoxic effect against hepatocellular carcinoma cell lines.  Ho CK, Huang YL, Chen CC.

3 Free Radic Res. 1995 Aug;23(2):175-84.   Mangostin inhibits the oxidative modification of human low density lipoprotein.  Williams P, Ongsakul M, Proudfoot J, Croft K, Beilin L.

 

Wolfberry (Lycium barbarum)

An important source of micronutrients as well as polysaccharides that protect the body against cellular damage.

            For thousands of years, Chinese healers used the fruit from the Wolfberry bush to strengthen the eyes, liver, kidneys, and build healthy circulatory and immune systems.  This berry is highly valued, not only for its outstanding nutrient value, but because it's wonderfully sweet and tangy taste.  Wolfberry contains nineteen amino acids, twenty-one important trace minerals, beta-carotene, vitamin C, and an unusually high amount of protein.  One of the key constituents of wolfberry is lycium barbarum polysaccharide (LBP)1 which has demonstrated the ability to protect the body against cellular damage2 as well as promote healthy cell growth.

 

1 Zhong Yao Cai. 2004 Aug;27(8):599-600[The study on the effect of LBP on cleaning hydroxygen free radical by EPR technique], Ni H, Qing D, Kaisa S, Lu J.

 

2 Int Immunopharmacol. 2004 Apr;4(4):563-9. Immunomodulation and antitumor activity by a polysaccharide-protein complex from Lycium barbarum.  Gan L, Hua Zhang S, Liang Yang X, Bi Xu H.

 

Sea Buckthorn* (Hippophae rhamnoides)

One of the best known natural sources of vitamins A, C, E, B vitamins, folic acid, essential fatty acids, bioflavonoids, phytosterols, and other micronutrients.

* This ingredient may not be included dependant on individual countries regulations.

            Ancient healers from India, Greece, Persia, and Germany harvested the berries from Sea Buckthorn to promote healthy skin and circulatory system.  This thorny shrub grows in dry regions often in coastal areas.  Sea Buckthorn berries are one of the best known natural sources of vitamins A,C,E, beta carotenes, and are rich in several B vitamins, folic acid, essential fatty acids, bioflavonoids, phytosterols, phenols, and many micronutrients.  Sea buckthorn has been shown to have a potent antioxidant activity1,2  mainly attributed to its bioflavonoid and vitamin C content3.

1 J Agric Food Chem. 2004 Dec 1;52(24):7264-71. Inhibition of cancer cell proliferation in vitro by fruit and berry extracts and correlations with antioxidant levels.  Olsson ME, Gustavsson KE, Andersson S, Nilsson A, Duan RD.  Department of Crop Science, Swedish University of Agricultural Sciences

2 Zhong Yao Cai. 2003 Dec;26(12):875-7. [Study on effect of flavonoids from oil-removed seeds of Hippophae rhamnoides on inducing apoptosis of human hepatoma cell], Sun B, Zhang P, Qu W, Zhang X, Zhuang X, Yang H.

3 J Agric Food Chem. 2003 Jul 16;51(15):4233-9. Structure-antioxidant efficiency relationships of phenolic compounds and their contribution to the antioxidant activity of sea buckthorn juice. Rosch D, Bergmann M, Knorr D, Kroh LW.

Grape (extract, seeds, and skin) (Vitis vinifera, spp.)

Rich in bioflavonoids and other phytochemicals that have powerful antioxidant properties.

            For years now, scientists from around the world have been puzzled by the phenomenon known as the French Paradox. What they observed was that although theFrench consume more than three times as much saturated fat as most other countries (in the form of butter, cream, and other high-fat ingredients), their rates of obesity and heart disease are surprisingly low. Clinical studies indicate that the consumption of grapes and wine by the French are responsible for their better health1,4 .  Scientists have measured the health properties of grapes and found that they contain the vitamins A, B and C, as well as thirteen minerals essential to human life.  Grape seed extract (another ingredient in Zambroza) is rich in bioflavonoids2 , phytochemicals that have powerful antioxidant properties which also help improve blood circulation, enhance the immune system3,4 , and strengthen blood vessels.

 

1 Mol Nutr Food Res. 2005 Feb;49(2):159-74. Dietary proanthocyanidins: Occurrence, dietary intake, bioavailability, and protection against cardiovascular disease.  Rasmussen SE, Frederiksen H, Struntze Krogholm K, Poulsen L.

 

2 Neoplasia. 2005 Jan;7(1):24-36. Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathways.  Roy AM, Baliga MS, Elmets CA, Katiyar SK., Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL

 

3 Yao Xue Xue Bao. 2004 Nov;39(11):869-75. [Isolation and structure identification of grape seed polyphenols and its effects on oxidative damage to cellular DNA], Fan PH, Lou HX.  College of Pharmacy, Shandong University

 

4Arch Latinoam Nutr. 2004 Jun;54(2 Suppl 1):79-82.  Wine in Mediterranean Diet], Lamuela-Raventos RM, Andres-Lacueva C.  Departament de Nutricio i Bromatologia, CERTA, Facultat de Farmacia, Universitat de Barcelona, Espana.

 

4Atherosclerosis. 1999 Jan;142(1):139-49. Proanthocyanidin-rich extract from grape seeds attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits.  Yamakoshi J, Kataoka S, Koga T, Ariga T.  Research and Development Division, Kikkoman Corporation, Noda City, Chiba Pref, Japan.

 

Raspberry (Rubus idaeus)

Contains many important phytonutrients including ellagic acid which helps promote a healthy cardiovascular system and helps the body maintain healthy capillaries in the eyes and brain.

Considered by many one of the best tasting members of the berry family, these intensely flavored and highly fragrant berries were first harvested by the early Greeks centuries ago.  Raspberries are among the most nutritious fruits on the planet. They are densely packed with potent phytochemicals that improve health and provide needed energy.   Raspberries are an excellent source of manganese, vitamin C, magnesium, potassium and B vitamins.  They also contain bioflavonoids called anthrocyanins which act as antioxidants1,2  .  One of the key constituents of raspberries is another antioxidant called ellagic acid.  Ellagic acid helps promote a healthy cardiovascular system and helps the body maintain healthy capillaries in the eyes and brain.   

1 J Agric Food Chem. 2002 Aug 28;50(18):5191-6. Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties.  Mullen W, McGinn J, Lean ME, MacLean MR, Gardner P, Duthie GG, Yokota T, Crozier A.  Plant Products and Human Nutrition Group, Graham Kerr Building, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, United Kingdom.

 

2 J Agric Food Chem. 2002 May 8;50(10):2926-30.  Antioxidant and antiproliferative activities of raspberries.  Liu M, Li XQ, Weber C, Lee CY, Brown J, Liu RH.

 

Blueberries (Vacinnium spp.)

One of the best natural sources of a bioflavonoid called anthocyanin which helps the body build strong veins and fights the effects of premature aging.

Famous for their mildly sweet and tangy flavor, blueberries are literally bursting with nutrition. Blueberries contain over forty compounds that have antioxidant properties1. What gives the blueberry its deep blue hue is a pigment called anthocyanin which makes it one of the healthiest food choices in the fight against premature aging.  Anthocyanin is a potent antioxidant.  Blueberries are also full of fiber, vitamins A and C, iron, and folic acid.  Studies done on blueberries show that they may strengthen eyesight and help maintain a healthy urinary tract.  Research also suggests that consuming blueberries each day improves balance, coordination, and short-term memory2   Blueberries have also been found to strengthen capillaries and help the body maintain healthy levels of cholesterol.3

 

1 J Med Food. 2004 Winter;7(4):450-5 Antimutagenic activity of berry extracts.  Hope Smith S, Tate PL, Huang G, Magee JB, Meepagala KM, Wedge DE, Larcom LL.  Department of Microbiology, Clemson University, Clemson, SC

 

2 Am J Clin Nutr. 2005 Jan;81(1 Suppl):313S-316S.  Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds.  Joseph JA, Shukitt-Hale B, Casadesus G.  US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, and the Institute of Pathology, Case Western Reserve University

 

3 Planta Med 1996 Jun;62(3):212-6.  . In vitro anticancer and cholesterol lowering activity of fruit extracts from Vaccinium species. Bomser J, Madhavi DL

 

Apple Extract (Malus sylvestris, M. domestica )

Rich in phenols and quercitin which help the body maintain proper cell growth, support the circulatory system, and immune system.

            Have you ever heard the old saying "an apple a day keeps the doctor away."  or "All the vitamins are in the peel of the fruit", recent scientific studies have found that both old saying are completely true.  Our scientists found that a combination of apples along with apple skins are very high in antioxidant compounds called phenols1,2   Phenols help the body maintain proper cell growth and also support the circulatory system. These phenols prevent the oxidation of the bad cholesterol in fat which causes premature aging in cells as well as other damage.  The bioflavonoids found in apples (especially the skins) have been extensively researched and found to help the body maintain a healthy circulatory system3,4. Apple skins contain a potent antioxidant bioflavonoid called quercitin.  Quercitin becomes especially potent when it teams up with other antioxidants to bolster the body’s immune defenses.  Quercitin has also been found to have an anti-inflammatory effect on the body.

 

1 J Agric Food Chem. 2005 Feb 23;53(4):928-34. Phenolic Profile, Antioxidant Property, and Anti-influenza Viral Activity of Chinese Quince (Pseudocydonia sinensis Schneid.), Quince (Cydonia oblonga Mill.), and Apple (Malus domestica Mill.) Fruits.  Hamauzu Y, Yasui H, Inno T, Kume C, Omanyuda M.

 

2 Biofactors. 2004;22(1-4):311-4. Characteristics and physiological functions of polyphenols from apples.

Akazome Y.  Fundamental Research Laboratory, Asahi Breweries, Ltd

 

3 Agric Food Chem. 2003 Mar 12;51(6):1676-83 Apple peels as a value-added food ingredient.

Wolfe KL, Liu RH.  Institute of Comparative and Environmental Toxicology, Cornell University, Ithaca, New York 

 

4 Nutr J. 2004 May 12;3(1):5. Apple phytochemicals and their health benefits.  Boyer J, Liu RH.  Department of Food Science and Institute of Comparative and Environmental Toxicology, Cornell University

 

Green Tea Extract  (Camellia sinensis)  

Contains a high amount of a family of antioxidants called polyphenols which help the body maintain healthy levels of cholesterol and protect against free radical damage.

            The Chinese have known about the medicinal benefits of green tea for over 4,000 years.  Today, scientific research in both Asia and the West are providing hard evidence for the health benefits long associated with drinking green tea1. For example, one recently published study found that that drinking green tea increased the body's natural resistance to "out of control cell growth" by  nearly sixty percent. There is also research indicating that drinking green tea lowers total cholesterol levels, as well as improving the ratio of good (HDL) cholesterol to bad (LDL) cholesterol and Green teas ability to support the digestive system2,3.  Most of the benefits of consuming green tea come from a family of antioxidants called polyphenols4,5.

 

1 J Nutr Biochem. 2005 Jan;16(1):1-8. Antiangiogenic properties of natural polyphenols from red wine and green tea.  Oak MH, El Bedoui J, Schini-Kerth VB.

 

2 J Agric Food Chem. 2002 Jun 5;50(12):3549-52. Antioxidative activity of green tea polyphenol in cholesterol-fed rats.  Yokozawa T, Nakagawa T, Kitani K.

 

3 Eur J Pharmacol. 2004 Oct 1;500(1-3):177-85. Pharmacological effects of green tea on the gastrointestinal system.  Koo MW, Cho CH.  Department of Pharmacology, Faculty of Medicine, The University of Hong Kong

 

4 Biofactors. 2004;22(1-4):135-40. Anti-obesity actions of green tea: Possible involvements in modulation of the glucose uptake system and suppression of the adipogenesis-related transcription factors.  Ashida H, Furuyashiki T, Nagayasu H, Bessho H, Sakakibara H, Hashimoto T, Kanazawa K.  Department of Biofunctional Chemistry, Faculty of Agriculture, Kobe University

 

5 J Environ Pathol Toxicol Oncol. 1999;18(3):147-58. Antimutagenic/antioxidant activity of green tea components and related compounds.  Pillai SP, Mitscher LA, Menon SR, Pillai CA, Shankel DM.  Department of Medicinal Chemistry and Molecular Bioscience, University of Kansas, Lawrence